Ganoderma tsugae

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(801) Chen, M.L. & B.F. Lin, 2007.  "Effects of triterpenoid-rich extracts of Ganoderma tsugae on airway hyperreactivity and Th2 responses in vivo."  Int Arch Allergy Immunol.  143(1):21-30. Epub 2006 Dec 22.

(802) Lin, J.Y., M.L. Chen & B.F. Lin, 2006.  "Ganoderma tsugae in vivo modulates Th1/Th2 and macrophage responses in an allergic murine model.  Food Chem Toxicol.  Dec;44(12):2025-32. Epub 2006 Jul 12.

(803) Lin, J.Y., M.L. Chen, B.L. Chiang & B.F. Lin, 2006  "Ganoderma tsugae supplementation alleviates bronchoalveolar inflammation in an airway sensitization and challenge mouse model."  Int Immunopharmacol.   Feb;6(2):241-51. Epub 2005 Aug 30.

(804) Hung, W.S., W.F. Lai, B. Leu, C.H. Su, C.L. Fang & Y.H. Tsai, 2004.   "Effect of SACCHACHITIN on keratinocyte proliferation and the expressions of type I collagen and tissue-transglutaminase during skin wound healing."  J Biomed Mater Res B Appl Biomater.  Jul 15;70(1):122-9.

(805) Hung, W.S., C.L. Fang, C.H. Su, W.F. Lai, Y.C. Chang & Y.H. Tsai, 2001.   "Cytotoxicity and immunogenicity of SACCHACHITIN and its mechanism of action on skin wound healing."  J Biomed Mater Res.  Jul;56(1):93-100.

(806) Su, C.H., C.S. Sun, S.W. Juan, C.H. Hu, W.T. Ke & M.T. Sheu, 1997.   "Fungal mycelia as the source of chitin and polysaccharides and their applications as skin substitutes."  Biomaterials.   Sep;18(17):1169-74.

(807) Su, C.H., C.S. Sun, S.W. Juan, H.O. Ho, C.H. Hu & M.T. Sheu, 1999.   "Development of fungal mycelia as skin substitutes: effects on wound healing and fibroblast."  Biomaterials.  Jan;20(1):61-8.

(808) Gan, K.H., Y.F. Fann, S.H. Hsu, K.W. Kuo & C.N. Lin, 1998.   "Mediation of the cytotoxicity of lanostanoids and steroids of Ganoderma tsugae through apoptosis and cell cycle."  J Nat Prod.   Apr;61(4):485-7.

(809) Zhang, J., G. Wang, H. Li, C. Zhuang, T. Mizuno, H. Ito, H. Mayuzumi, H. Okamoto & J. Li, 1994.  "Antitumor active protein-containing glycans from the Chinese mushroom songshan lingzhi, Ganoderma tsugae mycelium."  Biosci Biotechnol Biochem.  Jul;58(7):1202-5.

(810) Wang, G., J. Zhang, T. Mizuno, C. Zhuang, H. Ito, H. Mayuzumi, H. Okamoto & J. Li, 1993.  "Antitumor active polysaccharides from the Chinese mushroom Songshan lingzhi, the fruiting body of Ganoderma tsugae."  Biosci Biotechnol Biochem.  Jun;57(6):894-900.

(811) Peng, Y., L. Zhang, F. Zeng & Y. Xu, 2003.  "Structure and antitumor activity of extracellular polysaccharides from mycelium."  Carbohydrate Polymers  Volume 54, Issue 3, November, Pages 297-303

(812) Peng, Y., L. Zhang, F. Zeng, J.F. Kennedy, 2005.  "Structure and antitumor activities of the water-soluble polysaccharides from Ganoderma tsugae mycelium."  Carbohydrate Polymers  Volume 59, Issue 3, 18 February, Pages 385-392

(813) Liao, C.H., Y.M. Hsiao, C.P. Hsu, M.Y. Lin, J.C. Wang, Y.L. Huang & J.L. Ko, 2006.  "Transcriptionally mediated inhibition of telomerase of fungal immunomodulatory protein from Ganoderma tsugae in A549 human lung adenocarcinoma cell line."  Mol Carcinog.  Apr;45(4):220-9.

(814) Liao, C.H., Y.M. Hsiao, G.T. Sheu, J.T. Chang, P.H. Wang, M.F. Wu, G.J. Shieh, C.P. Hsu & J.L Ko, 2007.  "Nuclear translocation of telomerase reverse transcriptase and calcium signaling in repression of telomerase activity in human lung cancer cells by fungal immunomodulatory protein from Ganoderma tsugae."   Biochem Pharmacol.  Nov 15;74(10):1541-54. Epub 2007 Jul 22.

(815) Liao, C.H., Y.M. Hsiao, C.H. Lin, C.S. Yeh, J.C. Wang, C.H. Ni, C.P. Hsu & J.L. Ko, 2008.  "Induction of premature senescence in human lung cancer by fungal immunomodulatory protein from Ganoderma tsugae."  Food Chem Toxicol.  May;46(5):1851-9. Epub 2008 Feb 2.

(816) Yue, G.G., K.P. Fung, G.M. Tse, P.C. Leung & C.B. Lau, 2006.   "Comparative studies of various ganoderma species and their different parts with regard to their antitumor and immunomodulating activities in vitro."  J Altern Complement Med.  Oct;12(8):777-89.

(817) Wang, P.H., S.F. Yang, G.D. Chen, C.P. Han, S.C. Chen, L.Y. Lin & J.L. Ko, 2007.  "Human nonmetastatic clone 23 type 1 gene suppresses migration of cervical cancer cells and enhances the migration inhibition of fungal immunomodulatory protein from Ganoderma tsugae."  Reprod Sci.   Jul;14(5):475-85.

(818) Chen, C.F., X.T. Yang, X.Q. Li, K. Mi & Q.Y. Yang, 2007.  "A comparison study on the physical/chemical properties and immunomodulatory activities of mycelial polysaccharide extracts from five Ganoderma species."  Wei Sheng Wu Xue Bao.  Aug;47(4):628-33.

(819) Jinn, T.R., C.M. Wu, W.C. Tu, J.L. Ko & J.T. Tzen, 2006.   "Functional expression of FIP-gts, a fungal immunomodulatory protein from Ganoderma tsugae in Sf21 insect cells."  Biosci Biotechnol Biochem.   Nov;70(11):2627-34. Epub 2006 Nov 7.

(820) Gao, X.X., X.F. Fei, B.X. Wang, J. Zhang, Y.J. Gong, M. Minami, T. Nagata & T. Ikejima, 2000.  "Effects of polysaccharides (FI0-b) from mycelium of Ganoderma tsugae on proinflammatory cytokine production by THP-1 cells and human PBMC (I)."  Acta Pharmacol Sin.  Dec;21(12):1179-85.

(821) Gao, X.X., B.X. Wang, X.F. Fei, J. Zhang, Y.J. Gong, M. Minami, T. Nagata & T. Ikejima, 2000.  "Effects of polysaccharides (FI0-c) from mycelium of Ganoderma tsugae on proinflammatory cytokine production by THP-1 cells and human PBMC (II)."  Acta Pharmacol Sin.  Dec;21(12):1186-92.

(822) Lin, W.H., C.H. Hung, C.I. Hsu & J.Y. Lin, 1997.  "Dimerization of the N-terminal amphipathic alpha-helix domain of the fungal immunomodulatory protein from Ganoderma tsugae (Fip-gts) defined by a yeast two-hybrid system and site-directed mutagenesis."  J Biol Chem.  Aug 8;272(32):20044-8.

(823) Hsiao, YM, YL Huang, SC Tang, GJ Shieh, JY Lai, PH Wang, TH Ying & JL Ko, 2008.  "Effect of a fungal immunomodulatory protein from Ganoderma tsugae on cell cycle and interferon-gamma production through phosphatidylinositol 3-kinase signal pathway."  Process Biochemistry.  43(4):423-430

(824) Won, S.J., M.T. Lin & W.L. Wu, 1992.  "Ganoderma tsugae mycelium enhances splenic natural killer cell activity and serum interferon production in mice."  Jpn J Pharmacol.  59(2):171-6.

(825) Ko, H.H., C.F. Hung, J.P. Wang & C.N. Lin, 2008.  "Antiinflammatory triterpenoids and steroids from Ganoderma lucidum and G. tsugae."   Phytochemistry.  69(1):234-9.

(826) Wu, Y.W., K.D. Chen & W.C. Lin, 2004.  "Effect of Ganoderma tsugae on chronically carbon tetrachloride-intoxicated rats."  Am J Chin Med.  32(6):841-50.

(827) Mau, J.L., H.C. Lin & C.C. Chen, 2002.  "Antioxidant properties of several medicinal mushrooms."  J Agric Food Chem.  50(21):6072-7.

(828) Tseng, YH, JH Yang & JL Mau, 2008.  "Antioxidant properties of polysaccharides from Ganoderma tsugae."  Food Chemistry   107(2):732-738

(829) Mau, JL, SY Tsai, YH Tseng & SJ Huang, 2005.  "Antioxidant properties of methanolic extracts from Ganoderma tsugae."  Food Chemistry  93(4):641-649

(830) Mau, JL, SY Tsai, YH Tsen & SJ Huang, 2005.  "Antioxidant properties of hot water extracts from Ganoderma tsugae Murrill."   LWT - Food Science and Technology  38(6):589-597

(831) Yen, GC, JY Wu, 1999.  "Antioxidant and radical scavenging properties of extracts from Ganoderma tsugae."  Food Chemistry   65(3):375-379